Fascinating comparison of suffering across religious, artistic, and philosophical traditions.
May I suggest adding science fiction's take on the subject?
In the Star Trek (the original series, don't even start with that next generation nonsense) episode "I, Mudd" (S2 E8 https://memory-alpha.fandom.com/wiki/I,_Mudd_(episode)), the Enterprise crew encounters a planet inhabited by androids whose plan it is to "serve" humans until they become completely dependent upon the androids. "Their aggressive and acquisitive instincts will be under our control. We shall… take care of them."
This care includes access to advanced knowledge and tools and even virtual immortality through transference of consciousness into android bodies.
But, attracted as they are to the possibilities, the crew soon realizes (well, Kirk hammers the point home in ... yet ANOTHER ... IMPASSIONED ... soliloquy) that life without struggle is, as you have observed, without meaning.
The Midas Plague, originally a short story by Frederik Pohl, describes one possible future, where "the richer you are the less you are forced to consume" (https://www.goodreads.com/en/book/show/18370319).
Another excellent imagining of humanity's adaptation to a post-scarcity utopian future can be found in Iain M. Banks' unparalleled "Culture" novels (https://en.wikipedia.org/wiki/Culture_series).
Sometimes a good way to understand something more deeply is to imagine the lack or reverse of it, and these stories are good examples of this technique and dealing with this important topic.
Thank you for sharing your thoughts on this!